FB2026_02 , released June 18, 2026
Allele: Dmel\Gr28aUAS.cDa
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General Information
Symbol
Dmel\Gr28aUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Delventhal
FlyBase ID
FBal0325877
Feature type
allele
Associated gene
Dmel\Gr28a
Associated Insertion(s)
Carried in Construct
P{UAS-Gr28a.D}
Key Links
Transgenic product class
cDNA
(Delventhal and Carlson, 2016)
wild_type
(Delventhal and Carlson, 2016)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Delventhal and Carlson, 2016)
wild_type
(Delventhal and Carlson, 2016)
Mutagen
in vitro construct
(Delventhal and Carlson, 2016)
Progenitor genotype
Carried in construct
P{UAS-Gr28a.D}
Cytology
Description

UASt regulatory sequences drive expression of Gr28a cDNA (from proboscis, legs and larvae).

(Delventhal and Carlson, 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gr28a
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Gr28aScer\UAS.cDa under the control of Scer\GAL4Gr89a.2 leads to the following electrophysiological response changes of labellar sensilla to bitter tastants, as compared to controls: I-a sensilla display a significantly increased response to (-)-lobeline HCl; I-b sensilla display a novel and a significantly increased response to Saponin and Theophylline, respectively; S-a sensilla display significantly decreased responses to Aristolochic acid, Umbelliferone, Denatonium benzoate and Berberine chloride; these labellar sensilla types display no significant electrophysiological response changes to Rotenone, N,N-Diethyl-m-toluamide, Escin, Gossypol, Theobromine, Caffeine, Cucurbitacin I hydrate, D-(+)-sucrose octaacetate, Azadirachtin, Myricetin, Strychnine nitrate salt, Coumarin, Sparteine sulfate salt and Quinine.

      (Delventhal and Carlson, 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The expression of Gr28aScer\UAS.cDa under the control of Scer\GAL4Gr89a.2 leads to Gr59cΔ homozygous labellar I-a sensilla displaying novel electrophysiological responses to Coumarin and Azadirachtin, significant enhancements of their novel responses to Caffeine, Umbelliferone and Theophylline, and significant increases in their responses to Saponin, Aristolochic acid and Strychnine nitrate salt.

      (Delventhal and Carlson, 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gr28aScer\UAS.cDa
      Gr28aUAS.cDa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Delventhal
      Secondary FlyBase IDs
        References (1)