FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\trpS936A.ninaE
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General Information
Symbol
Dmel\trpS936A.ninaE
Species
D. melanogaster
Name
FlyBase ID
FBal0326771
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
P[rh1-trpS936A]
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

A minimal ninaE promoter (-833 to +67) drives expression of a trp carrying the amino acid replacement S936A (preventing phosphorylation of this residue). ninaE 3'UTR sequences are also present.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Like wild-type, trp9 heterozygous flies carrying trpS936A.ninaE do not display oscillating voltage electroretinogram response upon constant light stimulation and the frequency response of light-adapted flies to oscillating light of gradually increasing frequencies is comparable to controls at both low and high stimulus frequencies. Dark-adapted flies show no significant changes in the onset of the frequency-locked response to oscillating light of low (10Hz) frequency, but unlike wild-type flies they display a quick (<0.3s) frequency-locked response also at high (70Hz) frequency (wild-type flies take about 8s). Light-adapted flies at high frequency show normal quick onset, same as wild-type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
trpS936A.ninaE
Name Synonyms
Secondary FlyBase IDs
    References (2)