FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\SmnS201A.v.Tag:FLAG
Open Close
General Information
Symbol
Dmel\SmnS201A.v.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0338034
Feature type
allele
Associated gene
Dmel\Smn
Associated Insertion(s)
Carried in Construct
M{Flag-vSmn.S201A}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Gray et al., 2018)
Progenitor genotype
Smnv.Tag:FLAG
(Gray et al., 2018)
Carried in construct
M{Flag-vSmn.S201A}
Cytology
Description

The amino acid replacement S201A has been introduced into the Smnv.Tag:FLAG transgene. This lesion is within the putative degron.

(Gray et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
Smn
Encoded product / tool
Smn
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  childhood spinal muscular atrophy
      CEA
      (Gray et al., 2018)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      SmnS201A.v.Tag:FLAG rescues SmnX7

      (Gupta et al., 2021)

      SmnS201A.v.Tag:FLAG rescues SmnX7

      (Gray et al., 2018)
      Comments

      SmnS201A.v.Tag:FLAG fully rescues the larval lethality of SmnX7 homozygotes.

      (Gray et al., 2018)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SmnS201A.v.T:Zzzz\FLAG
      SmnS201A.v.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)