FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Axn1511
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General Information
Symbol
Dmel\Axn1511
Species
D. melanogaster
Name
FlyBase ID
FBal0338128
Feature type
allele
Associated gene
Dmel\Axn
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Dai et al., 2017)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q687H.

(Dai et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:30,034,075..30,034,075 [+]
Nucleotide change:

G30034075T

Reported nucleotide change:

G2001T

Amino acid change:

Q687H | Axn-PA; Q687H | Axn-PB; Q681H | Axn-PC; Q641H | Axn-PD; Q635H | Axn-PF; Q681H | Axn-PG

Reported amino acid change:

Q687H

(Dai et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Axn1511/AxnS044230 transheterozygotes are lethal.

      Axn1511 follicle cell clones can be found in the normal polar/stalk region, or as small clones within the main body forming ectopic polar and stalk cells, or as large clones that form a continuous stalk with a single polar cell cluster, causing the egg chamber to appear to bud from the side; clones generated at later stages, however, do not show these defects. Mosaic border cell/polar cell clusters containing Axn1511 clones present increased polar cell and total cell numbers, as compared to controls.

      (Dai et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Separable from: a secondary lethal mutation located at chromosomal position 84B2-84C3.

      (Dai et al., 2017)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Axn1511
      (Dai et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)