FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\exdUAS.lacZ,Tag:NLS(SV40-largeT)
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General Information
Symbol
Dmel\exdUAS.lacZ,Tag:NLS(SV40-largeT)
Species
D. melanogaster
Name
FlyBase ID
FBal0340422
Feature type
allele
Associated gene
Dmel\exd
Associated Insertion(s)
Carried in Construct
P{UAS-exd.NLS-Βgal}
P{UAS-NLS-lacZ-exd}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Abu-Shaar et al., 1999, Abu-Shaar and Mann, 1998, Casares and Mann, 1998)
Progenitor genotype
exd1-376.UAS.Tag:MYC
(Abu-Shaar et al., 1999)
Carried in construct
P{UAS-exd.NLS-Βgal}
P{UAS-NLS-lacZ-exd}
Cytology
Description

UASt regulatory sequences drive expression of exd tagged at the N-terminal end with a nuclear localization signal (Tag:NLS(SV40-largeT)) and the lacZ reporter.

(Abu-Shaar and Mann, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
exd
Tagged with
lacZ
Tag:NLS(SV40-largeT)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4Dll-md23-mediated expression does not cause transformation of anal plates into antenna but does generate truncated legs.

      (Casares and Mann, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Constitutively nuclear form of exd.

      (Casares and Mann, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      exdScer\UAS-NLS.T:Ecol\lacZ
      exdScer\UAS-NLS.lacZ
      exdScer\UAS.T:Ecol\lacZ,T:SV40\nls-largeT
      exdScer\UAS.T:Ecol\lacZ,T:SV40\nls2
      exdUAS-NLS.lacZ
      exdUAS.lacZ,Tag:NLS(SV40-largeT)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0096944
      • FBal0089284
      References (4)