FB2026_02 , released June 18, 2026
Allele: Dmel\Glo1KO
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General Information
Symbol
Dmel\Glo1KO
Species
D. melanogaster
Name
FlyBase ID
FBal0341193
Feature type
allele
Associated gene
Dmel\Glo1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Moraru et al., 2018)
Mutagen
P-element activity
(Moraru et al., 2018)
Progenitor genotype
P{GT1}Glo1BG02656
(Moraru et al., 2018)
Cytology
Description

Imprecise excision of P{GT1}Glo1BG02656 results in a 1136nt deletion, covering the translation start site and first 3 exons of Glo1.

(Moraru et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  type 2 diabetes mellitus
      CEA
      (Moraru et al., 2018)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Glo1KO mutant adults display increased food intake and become obese but do not show obvious defects in patterning, size or developmental rate, as compared to controls.

      (Moraru et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Glo1KO
      (Moraru et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)