UASt regulatory sequences drive expression of cv-c that has been mutated to carry the amino acid replacement R601Q. The protein is tagged at the C-terminal end with Venus.
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Disease-implicated variant(s)
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Expressing cv-cR601Q.UAS.Venus under the control of Scer\GAL4en.PU has no effect on planar cell polarity in the embryonic epidermis, while expression under the control of Scer\GAL469B has no impact on salivary gland morphology in embryos.