FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AP-2σang-2
Open Close
General Information
Symbol
Dmel\AP-2σang-2
Species
D. melanogaster
Name
FlyBase ID
FBal0344945
Feature type
allele
Associated gene
Dmel\AP-2σ
Associated Insertion(s)
P{EP}AP-2σang-2
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Choudhury et al., 2016)
Mutagen
Delta2-3 transposase
(Choudhury et al., 2016)
Progenitor genotype
Associated Insertion(s)
P{EP}AP-2σang-2
Cytology
Description

Insertion of a P{EP} element approximately 147bp upstream of lncRNA:Hsrω. Transcription of lncRNA:Hsrω is unaffected, however, there is a severe reduction in the level of transcription of the AP-2σ gene compared to controls.

(Choudhury et al., 2016)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larval muscle 6/7 NMJs in AP-2σang-2/AP-2σang-7 transheterozygotes show significantly more and significantly smaller boutons, as compared to controls.

      (Choudhury et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      AP-2σang-2
      ang2
      (Choudhury et al., 2016)
      angur2
      (Choudhury et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)