FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hecadel
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General Information
Symbol
Dmel\hecadel
Species
D. melanogaster
Name
FlyBase ID
FBal0346093
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Cytology
Description

Deletion of hdc, generated by FLP-mediated recombination between FRT sites in P{XP}d05275 and PBac{RB}hdce03709.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The induction of (near) whole-eye hdcdel clones leads to significantly larger eyes than upon the induction of (near) whole-eye control clones.

hdcdel homozygous eye disc clones are much larger than their twin-spots under a protein-poor diet, but nor under nutrient rich diet. This correlates with adult eyes bearing hdcdel clones being mainly composed of mutant tissue and being significantly larger than controls under a protein-poor diet, but not under nutrient rich diet. hdcdel homozygous eye disc clone cells show accelerated cell cycle progression, as mutant second mitotic wave cells are more anterior than neighboring wild-type controls; this is more evident under a protein-poor diet.

Wing disc clones are larger than their twin-spots under a protein-poor diet.

Both hdcdel adult wing margin bristle and pupal retina clones do not show cell size changes compared to controls under both nutrient rich and protein-poor diets.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
hecadel
Name Synonyms
Secondary FlyBase IDs
    References (1)