FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gr22f1
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General Information
Symbol
Dmel\Gr22f1
Species
D. melanogaster
Name
FlyBase ID
FBal0346757
Feature type
allele
Associated gene
Dmel\Gr22f
Associated Insertion(s)
TI{TI}Gr22f1
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gene targeting by homologous recombination
(Sung et al., 2017)
Progenitor genotype
Associated Insertion(s)
TI{TI}Gr22f1
Cytology
Description

Most of the Gr22f coding region has been deleted. Sequence encoding a w+mW.hs marker has been inserted in place of the deleted sequence.

(Sung et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:1,755,468..1,756,451 [-]
Comment:

Most of the Gr22f coding region has been deleted by homologous recombination. Sequence encoding a w+mW.hs marker has been inserted in place of the deleted sequence. Position of deletion endpoints on reference sequence determined from reported primer sequences.

(Sung et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gr22f1 mutants show significantly reduced S-b sensilla responsiveness to the bitter chemical DEN, but not to the bitter chemicals LOB or BER, as compared to controls.

      (Sung et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Gr22f1
      (Poudel et al., 2017, Sung et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)