FB2026_03 , released September 17, 2026
Allele: Dmel\nAChRα6W337term
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General Information
Symbol
Dmel\nAChRα6W337term
Species
D. melanogaster
Name
FlyBase ID
FBal0346772
Feature type
allele
Associated gene
Dmel\nAChRα6
Associated Insertion(s)
Carried in Construct
Also Known As
dα6W337*
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Perry et al., 2015)
Progenitor genotype
Cytology
Description

Amino acid replacement: W337term.

(Perry et al., 2015)

Mutation is in exon 9, an exon common to all alternative splice isoforms.

(Perry et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:9,798,197..9,798,197 [-]
Nucleotide change:

G9798197A

Reported nucleotide change:

G?A

Amino acid change:

W337term | nAChRalpha6-PA; W337term | nAChRalpha6-PB; W337term | nAChRalpha6-PC; W352term | nAChRalpha6-PD; W366term | nAChRalpha6-PE; W337term | nAChRalpha6-PG; W337term | nAChRalpha6-PH

Reported amino acid change:

W337term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified).

(Perry et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
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      Human Disease Associations
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      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
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      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
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      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
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      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dα6W337*
      (Perry et al., 2015, Somers et al., 2015)
      nAChRα6W337term
      Name Synonyms
      Secondary FlyBase IDs
        References (2)