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General Information
Symbol
Dmel\Pink1UASp.GFP,Tag:Mito(Tom20)
Species
D. melanogaster
Name
FlyBase ID
FBal0347458
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASp regulatory sequences drive expression of Pink1 (coordinates 451-2166 of the gene). The protein is targeted to the mitochondrial outer membrane by fusion at its N-terminal end to Tom20, and is also tagged with GFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Females expressing Pink1UASp.GFP,Tag:Mito(Tom20) under the control of Scer\GAL4nos.PU exhibit a reduction in the mitochondrial DNA replication (EdU staining) in ovaries and lay eggs with significantly reduced mitochondrial content and hatching rate when compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Pink1UASp.GFP,Tag:Mito(Tom20)
Name Synonyms
Secondary FlyBase IDs
    References (1)