UAS regulatory sequences drive expression of the RBR-LDD region of LUBEL, mutated to carry a C2704A amino acid replacement (this results in a catalytically inactive protein).
Comments on Models/Modifiers Based on Experimental Evidence
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Disease-implicated variant(s)
Phenotypic Data
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Adults expressing LUBELRBR-LDD.C-A.UAS under the control of Scer\GAL4da.PU do not show changes in the mitotic index of the gut, as compared to controls.