FlyBase Allele Report: Dmel\l(3)80Fj[Z4577]

General Information

Symbol

Dmel\l(3)80Fj^Z4577

Species

D. melanogaster

Name

FlyBase ID

FBal0349094

Feature type

allele

Associated gene

Dmel\l(3)80Fj

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Syrzycka et al., 2019)

Progenitor genotype

Cytology

Description

Amino acid replacement: W1092term.

(Syrzycka et al., 2019)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3L:27,971,949..27,971,949 [-]

Nucleotide change:

G27971949A

Amino acid change:

W1092term | l(3)80Fj-PA

Reported amino acid change:

W1092term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Syrzycka et al., 2019)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage (with Df(3L)1-166)

(Syrzycka et al., 2019)

abnormal size | adult stage (with Df(3L)2-30)

(Syrzycka et al., 2019)

abnormal size | adult stage (with Df(3L)6B-29+Df(3R)6B-29)

(Syrzycka et al., 2019)

abnormal size | adult stage (with Df(3L)e54)

(Syrzycka et al., 2019)

abnormal size | adult stage (with In(3L)C90)

(Syrzycka et al., 2019)

abnormal size | adult stage (with l(3)80Fj^Z1261)

(Syrzycka et al., 2019)

lethal (with Df(3L)6B-29+Df(3R)6B-29)

(Syrzycka et al., 2019)

lethal (with Df(3L)9-56)

(Syrzycka et al., 2019)

lethal | recessive

(Syrzycka et al., 2019)

partially lethal - majority die (with Df(3L)1-166)

(Syrzycka et al., 2019)

partially lethal - majority die (with Df(3L)2-30)

(Syrzycka et al., 2019)

partially lethal - majority die (with Df(3L)e54)

(Syrzycka et al., 2019)

partially lethal - majority die (with In(3L)C90)

(Syrzycka et al., 2019)

partially lethal - majority die (with l(3)80Fj^Z1261)

(Syrzycka et al., 2019)

sterile (with l(3)80Fj^Z1261)

(Syrzycka et al., 2019)

viable (with Df(3L)FX53)

(Syrzycka et al., 2019)

viable (with Df(3L)Δ1AK)

(Syrzycka et al., 2019)

viable (with Df(3R)XM3)

(Syrzycka et al., 2019)

Phenotype Manifest In

macrochaeta (with Df(3L)1-166)

(Syrzycka et al., 2019)

macrochaeta (with Df(3L)2-30)

(Syrzycka et al., 2019)

macrochaeta (with Df(3L)6B-29+Df(3R)6B-29)

(Syrzycka et al., 2019)

macrochaeta (with Df(3L)e54)

(Syrzycka et al., 2019)

macrochaeta (with In(3L)C90)

(Syrzycka et al., 2019)

macrochaeta (with l(3)80Fj^Z1261)

(Syrzycka et al., 2019)

wing vein (with l(3)80Fj^Z1261)

(Syrzycka et al., 2019)

Detailed Description

Statement

Reference

CG17514^Z1261/CG17514^Z4577 escapers are sterile and display a Minute-like phenotype (thin bristles) as well as extra wing vein material.

CG17514^Z4577/Df(3L)6B-29+Df(3R)6B-29, CG17514^Z4577/Df(3L)1-166, CG17514^Z4577/Df(3L)e54, CG17514^Z4577/In(3L)C90 and CG17514^Z4577/Df(3L)2-30 escapers display a Minute-like phenotype (thin bristles).

(Syrzycka et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

81858

st¹ l(3)80Fj^Z4577/TM3, P{ActGFP}JMR2, Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG17514^Z4577

Z-4577

(Syrzycka et al., 2019)

l(3)80Fj^Z4577

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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