FB2026_02 , released June 18, 2026
Allele: Dmel\Zif1106
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General Information
Symbol
Dmel\Zif1106
Species
D. melanogaster
Name
FlyBase ID
FBal0351663
Feature type
allele
Associated gene
Dmel\Zif
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: L255Q.

    (Burguete et al., 2019)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:6,458,169..6,458,169 [+]
    Nucleotide change:

    T6458169A

    Amino acid change:

    L255Q | Zif-PA; L255Q | Zif-PB; L255Q | Zif-PC

    Reported amino acid change:

    L255Q

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

    (Burguete et al., 2019)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Zif1106/Zif1106 somatic clones of terminal tracheal cells form discontinuous tubes in third instar larvae.

        (Burguete et al., 2019)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        Zifunspecified

        (Burguete et al., 2019)
        Comments

        asthmatic1530 complements the Zif742 allele, but fails to complement Zif1106 (both Zif alleles have been shown to have a point mutation in the CG10267 transcription unit corresponding to Zif). It is not known whether Zif1106 also carries a mutation in the gene corresponding to the asthmatic locus, or whether asthmatic1530 and Zif1106 carry mutations in a third essential gene.

        (Burguete et al., 2019)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Zif1106
        asthmatic1106
        (Burguete et al., 2019)
        zifasthmatic1106
        (Burguete et al., 2019)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)