FB2026_02 , released June 18, 2026
Allele: Dmel\E(spl)m8-HLHGFP
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General Information
Symbol
Dmel\E(spl)m8-HLHGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0355293
Feature type
allele
Associated gene
Dmel\E(spl)m8-HLH
Associated Insertion(s)
Carried in Construct
M{GFP-E(spl)m8-HLH}
Key Links
Transgenic product class
genomic_DNA
(Trylinski et al., 2017)
wild_type
(Trylinski et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Trylinski et al., 2017)
wild_type
(Trylinski et al., 2017)
Mutagen
in vitro construct
(Trylinski et al., 2017)
Progenitor genotype
Carried in construct
M{GFP-E(spl)m8-HLH}
Cytology
Description

E(spl)m8-HLH from a BAC is tagged with GFP at the N-terminal end of the open reading frame.

(Trylinski et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
E(spl)m8-HLH
Encoded product / tool
E(spl)m8-HLH
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      mesonotum | restricted
      (Couturier et al., 2019)
      prepupal stage P3
      mesonotum | restricted
      (Couturier et al., 2019)
      Additional Information
      Statement
      Reference

      E(spl)m8-HLH is coexpressed with E(spl)mδ-HLH and E(spl)m7-HLH in a subset of cells within proneural stripes. It is detected in proneural stripe cells with low/intermediate levels of ac.

      (Couturier et al., 2019)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      E(spl)m8-HLHGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)