FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\snzKO
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General Information
Symbol
Dmel\snzKO
Species
D. melanogaster
Name
FlyBase ID
FBal0355588
Feature type
allele
Associated gene
Dmel\snz
Associated Insertion(s)
TI{TI}snzKO
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - molecular evidence

    (Ugrankar et al., 2019)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    TI{TI}snzKO
    Cytology
    Description

    The entire snz open reading frame has been deleted; sequence from 188bp upstream of the start codon to 83bp after the stop codon has been replaced with a loxP cassette that contains a w+* marker.

    (Ugrankar et al., 2019)
    Allele components
    Component
    Use(s)
    Also carries
    loxP
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    delins
    X:7,912,676..7,917,406 [+]
    Comment:

    The entire snz open reading frame has been deleted; sequence from 188bp upstream of the start codon to 83bp after the stop codon has been replaced with a loxP cassette that contains a w+* marker.

    (Ugrankar et al., 2019)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        snzKO larvae manifest no obvious phenotype under ambient conditions, but fat body cells exhibit drastic variability in peripheral lipid droplets; there are changes in cytoplasmic medial lipid droplet size.

        (Ugrankar et al., 2019)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        SNZKO
        (Ugrankar et al., 2019)
        snzKO
        Δsnz
        (Lauzier et al., 2022)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)