FB2026_03 , released September 17, 2026
Allele: Dmel\Obp83b+t10.6
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General Information
Symbol
Dmel\Obp83b+t10.6
Species
D. melanogaster
Name
FlyBase ID
FBal0357194
Feature type
allele
Associated gene
Dmel\Obp83b
Associated Insertion(s)
Carried in Construct
P{Obp83b.Obp83a.10.6}
Key Links
Transgenic product class
genomic_DNA
(Scheuermann and Smith, 2019)
wild_type
(Scheuermann and Smith, 2019)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Scheuermann and Smith, 2019)
wild_type
(Scheuermann and Smith, 2019)
Mutagen
in vitro construct
(Scheuermann and Smith, 2019)
Progenitor genotype
Carried in construct
P{Obp83b.Obp83a.10.6}
Cytology
Description

10.6kb genomic fragment that encompasses both Obp83a and Obp83b transcription units.

(Scheuermann and Smith, 2019)
Allele components
Component
Use(s)
Regulatory region(s)
Obp83b
Encoded product / tool
Obp83b
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Individuals bearing two copies of the Obp83a+t10.6,Obp83b+t10.6 genomic transgene show similar deactivation of Or47b, Or83c and Or67d neurons upon stimulation with trans-2-hexenal, farnesol and cVA, respectively, as compared to controls.

      (Scheuermann and Smith, 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A Obp83a+t10.6,Obp83b+t10.6 genomic transgene rescues the following defects in Df(3R)OS-EF- mutant trichoid/intermediate sensilla neurons: the increased spontaneous activity of Or47b neurons, as well as their decreased response (and delayed deactivation) to the odorant trans-2-hexenal; the increased spontaneous activity of Or88a/Or65abc neurons; the increased response (and delayed deactivation) of Or83c neurons to the odorant farnesol; the decreased response (and delayed deactivation) of at1 sensilla/Or67d neurons to the pheromone cVA.

      (Scheuermann and Smith, 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Obp83b+t10.6
      Name Synonyms
      Secondary FlyBase IDs
        References (1)