FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: TEV\NIaT173V.LexAop2.Tag:M(rCd2),Tag:MYC
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General Information
Symbol
TEV\NIaT173V.LexAop2.Tag:M(rCd2),Tag:MYC
Species
P. Tobacco etch virus
Name
FlyBase ID
FBal0365169
Feature type
allele
Associated gene
TEV\NIa
Associated Insertion(s)
Carried in Construct
P{LexAop2-TEVT173V.CD2.P10}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cachero et al., 2020)
Progenitor genotype
TEV\NIaT173V.RSRT.Flp1.LexAop2.Tag:M(rCd2),Tag:MYC
(Cachero et al., 2020)
Carried in construct
P{LexAop2-TEVT173V.CD2.P10}
Cytology
Description

The removable cassette present present in TEV\NIaT173V.RSRT.Flp1.LexAop2.Tag:M(rCd2),Tag:MYC has been removed, leaving behind a single RSRT site (that is innocuous). As a result, lexAop (LexAop2) drives expression of a coding sequence encoding TEVp(T173V) plus a transmembrane sequence (Tag:M(rCd2)) that targets TEVp(T173V) to the cell surface. The N-terminus of the coding sequence has the C. elegans PAT3 signal peptide sequence for endoplasmic reticulum targeting, while the C-terminus has the Kir2.1 ER export signal to improve trafficking to the plasma membrane, followed by the P10 3' UTR. Tag:MYC has been introduced in between the TEVp(T173V) and Tag:M(rCd2) sequence. Used in the first (release) step of the BacTrace system.

(Cachero et al., 2020)
Allele components
Component
Use(s)
Regulatory region(s)
lexAop
Encoded product / tool
TEVp(T173V)
Tagged with
Tag:M(rCd2)
Tag:MYC
Also carries
RSRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TEV\NIaT173V.LexAop2.Tag:M(rCd2),Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)