FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sliGPI-Myc
Open Close
General Information
Symbol
Dmel\sliGPI-Myc
Species
D. melanogaster
Name
FlyBase ID
FBal0365216
Feature type
allele
Associated gene
Dmel\sli
Associated Insertion(s)
TI{TI}sliGPI-Myc
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gene targeting by homologous recombination
(Kellermeyer et al., 2020)
Progenitor genotype
Associated Insertion(s)
TI{TI}sliGPI-Myc
Cytology
Description

The endogenous sli locus has been replaced with full-length sli that is tagged at the C-terminal end with a Tag:GPI(Unk) anchor (this tethers the protein to the plasma membrane).

(Kellermeyer et al., 2020)
Allele components
Component
Use(s)
Tagged with
Tag:GPI(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sliGPI-Myc homozygous embryos exhibit longitudinal axons collapsed onto the midline.

      (Kellermeyer et al., 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      sliGPI-Myc has abnormal neuroanatomy | embryonic stage phenotype, suppressible | partially by tok1/tok1

      (Kellermeyer et al., 2020)
      Suppressor of
      Phenotype Manifest In
      Suppressed by
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sliGPI-Myc
      Name Synonyms
      Secondary FlyBase IDs
        References (1)