FB2026_03 , released September 17, 2026
Allele: Dmel\pntP3.GFP
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General Information
Symbol
Dmel\pntP3.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0365937
Feature type
allele
Associated gene
Dmel\pnt
Associated Insertion(s)
Carried in Construct
PBac{GFP-pnt.P3}
Key Links
Transgenic product class
genomic_DNA
(Wu et al., 2020)
wild_type
(Wu et al., 2020)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Wu et al., 2020)
wild_type
(Wu et al., 2020)
Mutagen
in vitro construct
(Wu et al., 2020)
Progenitor genotype
Carried in construct
PBac{GFP-pnt.P3}
Cytology
Description

Genomic BAC clone (CH321-39L2) that encompasses pnt. A GFP tag has been inserted at the N-terminal end of the pnt P3 isoform.

(Wu et al., 2020)
Allele components
Component
Use(s)
Regulatory region(s)
pnt
Encoded product / tool
pnt
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      eye disc morphogenetic furrow
      (Wu et al., 2020)
      eye disc posterior to the morphogenetic furrow
      (Wu et al., 2020)
      photoreceptor R2 precursor cell
      (Wu et al., 2020)
      photoreceptor R5 precursor cell
      (Wu et al., 2020)
      photoreceptor R3 precursor cell
      (Wu et al., 2020)
      photoreceptor R4 precursor cell
      (Wu et al., 2020)
      photoreceptor R8 precursor cell
      (Wu et al., 2020)
      Additional Information
      Statement
      Reference

      The construct was used to report expression of the "PntP3" isoform, which corresponds to pnt-PD in FlyBase. It is expressed in an overlapping but distinct pattern from "PntP2" (pnt-PB). PntP3 expression is strongest in and immediately posterior to the morphogenetic furrow in third instar larval eye discs. Coexpression is observed in R2/R5 and R3/R4 photoreceptor pairs, in basal progenitors at the morphogenetic furrow and in cone cells. Complementary expression is detected posterior to the second mitotic wave in photoreceptors R1, R6, and R7, where PntP2 is high and PntP3 is low, and in apically localized nuclei at the morphogenetic furrow, including R8, where PntP3 is high and PntP2 is low.

      (Wu et al., 2020)
       
      Marker for
      Reflects expression of
      pnt
      (Wu et al., 2020)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pntP3.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)