FlyBase Allele Report: Dmel\Cby[c.121delC]

General Information

Symbol

Dmel\Cby^c.121delC

Species

D. melanogaster

Name

FlyBase ID

FBal0367231

Feature type

allele

Associated gene

Dmel\Cby

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Deletion (c.121delC) within the Cby locus; predicted to result in a truncated protein.

(Wu et al., 2020)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3R:21,868,369..21,868,369 [+]

Comment:

Deletion of a "C" residue early in the coding region of Cby leads to a frameshift.

(Wu et al., 2020)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

axoneme | spermatogenesis

(Wu et al., 2020)

centriole | spermatogenesis

(Wu et al., 2024)

microtubule | spermatogenesis

(Wu et al., 2024)

spermatocyte

(Wu et al., 2024)

Detailed Description

Statement

Reference

Cby^c.121delC spermatocytes show elongated primary axonemes (labelled by CG6652).

(Wu et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Cby^c.121delC, Cep162¹ has uncoordinated | adult stage phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep162¹ has abnormal behavior | larval stage phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep162¹ has decreased rate of adult locomotory behavior phenotype

(Wu et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

Cby^c.121delC has spermatocyte phenotype, enhanceable by Cep162¹

(Wu et al., 2024)

Cby^c.121delC has centriole | spermatogenesis phenotype, enhanceable by Cep162¹

(Wu et al., 2024)

Cby^c.121delC has microtubule | spermatogenesis phenotype, enhanceable by Cep162¹

(Wu et al., 2024)

Cby^c.121delC has axoneme | spermatogenesis phenotype, enhanceable by Rab8¹

(Wu et al., 2020)

Enhancer of

Statement

Reference

Cby^c.121delC is an enhancer of spermatocyte phenotype of Cep162¹

(Wu et al., 2024)

Cby^c.121delC is an enhancer of microtubule | spermatogenesis phenotype of Cep162¹

(Wu et al., 2024)

Cby^c.121delC is an enhancer of centriole | spermatogenesis phenotype of Cep162¹

(Wu et al., 2024)

Cby^c.121delC is an enhancer of cilium phenotype of Cep162¹

(Wu et al., 2024)

Other

Statement

Reference

Cby^c.121delC, Cep162¹ has spermatid phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep290^ΔC has adult antennal sense organ phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep162¹ has axoneme | absent phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep162¹ has cilium | P-stage | absent phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep162¹ has adult antennal sense organ | P-stage phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep290^ΔC has spermatocyte phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep290^ΔC has cilium phenotype

(Wu et al., 2024)

Cby^c.121delC, Cep290^ΔC has centriole | spermatogenesis phenotype

(Wu et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Cby^c.121delC

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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