FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\His4rΔ42
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General Information
Symbol
Dmel\His4rΔ42
Species
D. melanogaster
Name
FlyBase ID
FBal0367618
Feature type
allele
Associated gene
Dmel\His4r
Associated Insertion(s)
P{?EPgy2}His4rΔ42
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Faragó et al., 2021)
Mutagen
Delta2-3 transposase
(Faragó et al., 2021)
Progenitor genotype
P{EPgy2}His4rEY06726
(Faragó et al., 2021)
Associated Insertion(s)
P{?EPgy2}His4rΔ42
Cytology
Description

694bp deletion that removes the entire coding region of His4r; deletion breakpoints are 3R:14625816 and 3R:14626511 (release 6 genome), and a 29bp scar sequence containing remnants of the original P{EPgy2} insertion is also present at the site of the deletion. Generated by imprecise excision of P{EPgy2}His4rEY06726.

(Faragó et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:14,625,817..14,626,510 [+]
Comment:

A 694bp deletion resulting from the imprecise excision of P{EPgy2}His4rEY06726 removes the entire His4r coding region. 29bp of P element sequence remain at the site of the excision. The reported coordinates for the deletion refer to the bases flanking the deletion.

Inserted_sequence:

CATGATGAAATAACATTASTATTAGTATT

(Faragó et al., 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
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      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      His4rΔ42
      (Faragó et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)