FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CTCFΔ705-733-HA
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General Information
Symbol
Dmel\CTCFΔ705-733-HA
Species
D. melanogaster
Name
FlyBase ID
FBal0369970
Feature type
allele
Associated gene
Dmel\CTCF
Associated Insertion(s)
TI{TI}CTCFΔ705-733-HA
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Kyrchanova et al., 2021)
cre recombinase
(Kyrchanova et al., 2021)
Progenitor genotype
TI{TI}CTCFattP.mCh
(Kyrchanova et al., 2021)
Associated Insertion(s)
TI{TI}CTCFΔ705-733-HA
Cytology
Description

Genomic DNA has been re-integrated into the attP site in TI{TI}CTCFattP.mCh, reconstituting a CTCF locus that lacks the Cp190 interacting domain (amino acid residues 705-733) and which is tagged at the C-terminal end with three copies of Tag:HA. Some duplicated CTCF sequence (part of exon 3 through to the end of exon 4) is present downstream of the reconstituted locus, but this is not expressed, due to the presence of a SV40 polyadenylation signal between the reconstituted locus and the duplicated sequence. A single loxP site is present in the first intron.

(Kyrchanova et al., 2021)
Allele components
Component
Use(s)
Tagged with
Tag:HA
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CTCFΔ705-733-HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)