FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nordUAS.ag:HA,GFP
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General Information
Symbol
Dmel\nordUAS.ag:HA,GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0371879
Feature type
allele
Associated gene
Dmel\nord
Associated Insertion(s)
Carried in Construct
P{UAS-nord.HA.GFP}
Key Links
Transgenic product class
cDNA
(Yang et al., 2022)
wild_type
(Yang et al., 2022)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yang et al., 2022)
wild_type
(Yang et al., 2022)
Mutagen
in vitro construct
(Yang et al., 2022)
Progenitor genotype
Carried in construct
P{UAS-nord.HA.GFP}
Cytology
Description

UASt regulates expression of the coding sequence of nord fused with a C-terminal Tag:HA-GFP tag.

(Yang et al., 2022)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
nord
Tagged with
GFP
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of nordUAS.ag:HA,GFP under the control of Scer\GAL4nub-AC-62 results in a small wing; partial L5 and PCV loss is also observed, particularly at higher nordUAS.ag:HA,GFP expression levels (ie at 29[o]C).

      The expression from 78h prior to eclosion of nordUAS.ag:HA,GFP under the control of Scer\GAL4en-e16E (together with Gal80[ts] for the temporal control of expression) leads to posterior crossvein defects. 1 copy of nordUAS.ag:HA,GFP induces an ectopic posterior crossvein, 3 copies lead to loss of the posterior crossvein, 2 copies lead to a mixed phenotype and an ectopic anterior crossvein; Similar expression driven by Scer\GAL4hh.PU, also leads to posterior crossvein defects: 1 or two copies of nordUAS.ag:HA,GFP induces a mixed phenotype of loss/ectopic posterior crossvein, and an ectopic anterior crossvein.

      (Yang et al., 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      nordUAS.ag:HA,GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)