FB2026_03 , released September 17, 2026
Allele: Dmel\DroBtn-Ala
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General Information
Symbol
Dmel\DroBtn-Ala
Species
D. melanogaster
Name
FlyBase ID
FBal0375861
Feature type
allele
Associated gene
Dmel\Dro
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

wild-type allele

Mutagen
    Nature of the Allele
    Allele class

    wild-type allele

    (Hanson et al., 2022)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Represents the wild type allele encoding an Alanine at residue 52 in the C-terminus of the Drosocin precursor protein sequence, which is residue 10 in the mature C-terminal 'Buletin' peptide. (This residue is polymorphic across Drosophila strains, encoding either Threonine or Alanine - the D. melanogaster reference genome encodes the Threonine version.)

    (Hanson et al., 2022)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    sequence_variant
    2R:14,746,143..14,746,143 [+]
    Nucleotide change:

    A14746143G

    Amino acid change:

    T52A | Dro-PA; T52A | Dro-PB

    Reported amino acid change:

    T52A

    Comment:

    This residue is polymorphic across Drosophila strains, encoding either Threonine or Alanine - the D. melanogaster reference genome encodes the Threonine version.

    (Hanson et al., 2022)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        BtnAla
        (Hanson et al., 2022)
        DroBtn-Ala
        Name Synonyms
        Secondary FlyBase IDs
          References (1)