FlyBase Allele Report: Cbot\BoNT-C[LC.UAS.cHa]

General Information

Symbol

Cbot\BoNT-C^LC.UAS.cHa

Species

C. botulinum

Name

FlyBase ID

FBal0376719

Feature type

allele

Associated gene

Cbot\BoNT-C

Associated Insertion(s)

Carried in Construct

P{UAS-BoNT-C-LC.H}

Also Known As

UAS-BoNT-C

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Han et al., 2022)

Progenitor genotype

Carried in construct

P{UAS-BoNT-C-LC.H}

Cytology

Description

UASt regulatory sequences drive expression of BoNT-C-LC.

(Han et al., 2022)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

BoNT-C-LC

neuron inhibition tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology | larval stage, with Scer\GAL4^OK319

(Han et al., 2023)

Phenotype Manifest In

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^OK319

(Han et al., 2023)

motor neuron | larval stage, with Scer\GAL4^OK319

(Han et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Cbot\BoNT-C^LC.UAS.cHa, GluRIIA^PV3, Scer\GAL4^GMR27E09 has abnormal neurophysiology | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, Ecol\lexA^RapGAP1-OK6, Scer\GAL4^GMR27E09, VGlut1^lexAop.cHa has abnormal neurophysiology | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, Ecol\lexA^RapGAP1-OK6, Scer\GAL4^exex-Gal4, VGlut1^lexAop.cHa has abnormal neurophysiology | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIA^PV3, Scer\GAL4^exex-Gal4 has abnormal neurophysiology | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIB^SP5, Scer\GAL4^GMR27E09 has abnormal neurophysiology | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIB^SP5, Scer\GAL4^exex-Gal4 has abnormal neurophysiology | larval stage phenotype

(Han et al., 2023)

Phenotype Manifest In

Other

Statement

Reference

Cbot\BoNT-C^LC.UAS.cHa, GluRIIA^PV3, Scer\GAL4^GMR27E09 has embryonic/larval neuromuscular junction | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIB^SP5, Scer\GAL4^exex-Gal4 has embryonic/larval neuromuscular junction | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIB^SP5, Scer\GAL4^exex-Gal4 has type Is motor neuron | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, Ecol\lexA^RapGAP1-OK6, Scer\GAL4^GMR27E09, VGlut1^lexAop.cHa has embryonic/larval neuromuscular junction | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, Ecol\lexA^RapGAP1-OK6, Scer\GAL4^GMR27E09, VGlut1^lexAop.cHa has type Ib motor neuron | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, Ecol\lexA^RapGAP1-OK6, Scer\GAL4^exex-Gal4, VGlut1^lexAop.cHa has embryonic/larval neuromuscular junction | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, Ecol\lexA^RapGAP1-OK6, Scer\GAL4^exex-Gal4, VGlut1^lexAop.cHa has type Is motor neuron | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIA^PV3, Scer\GAL4^GMR27E09 has type Ib motor neuron | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIA^PV3, Scer\GAL4^exex-Gal4 has embryonic/larval neuromuscular junction | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIA^PV3, Scer\GAL4^exex-Gal4 has type Is motor neuron | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIB^SP5, Scer\GAL4^GMR27E09 has embryonic/larval neuromuscular junction | larval stage phenotype

(Han et al., 2023)

Cbot\BoNT-C^LC.UAS.cHa, GluRIIB^SP5, Scer\GAL4^GMR27E09 has type Ib motor neuron | larval stage phenotype

(Han et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Cbot\BoNT-C^LC.UAS.cHa

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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