FB2026_02 , released June 18, 2026
Allele: Dmel\fra::unc-5fra-cyto.UAS.Tag:HA,Tag:SS(wg)
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General Information
Symbol
Dmel\fra::unc-5fra-cyto.UAS.Tag:HA,Tag:SS(wg)
Species
D. melanogaster
Name
FlyBase ID
FBal0387473
Feature type
allele
Associated gene
fra::unc-5
Associated Insertion(s)
Carried in Construct
P{UAS-HA-unc-5::fra-cyto}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Long et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-HA-unc-5::fra-cyto}
Cytology
Description

UAS regulatory sequences drive expression of a chimeric protein in which the unc-5 cytoplasmic domain has been replaced by the cytoplasmic domain of fra (unc-5 amino acids 32-536 are fused via a Ser-Phe linker to fra amino acids 1101-1374). The coding sequence is tagged at the N-terminal end with the Tag:SS(wg) signal sequence followed by three copies of Tag:HA.

(Long et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
fra::unc-5
Tagged with
Tag:HA
Tag:SS(wg)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      fra::unc-5fra-cyto.UAS.Tag:HA,Tag:SS(wg)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)