FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: HPV16\E6UAS.cHa
Open Close
General Information
Symbol
HPV16\E6UAS.cHa
Species
A. Human papillomavirus type 16
Name
FlyBase ID
FBal0387743
Feature type
allele
Associated gene
HPV16\E6
Associated Insertion(s)
Carried in Construct
P{UAS-HPV16-E5-E6-E7}
Transgenic product class
wild_type
(Hashemi et al., 2022)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hashemi et al., 2022)
Mutagen
in vitro construct
(Hashemi et al., 2022)
Progenitor genotype
Carried in construct
P{UAS-HPV16-E5-E6-E7}
Cytology
Description

UAS regulatory sequences drive expression of a multicistronic transcript that encodes three open reading frames, each separated by a T2A linker (this results in separate translation of each protein) and codon optimized for expression in Drosophila. The encoded proteins are HPV16\E5 (tagged at the N-terminal end with Tag:HA), HPV16\E6 and HPV16\E7.

(Hashemi et al., 2022)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
HPV16\E6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  carcinoma
      CEA with Hsap\UBE3AUAS.cRa
      (Hashemi et al., 2022)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      HPV16\E6UAS.cHa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)