FB2026_02 , released June 18, 2026
Allele: Dmel\TTLL5MI01917-Ex
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General Information
Symbol
Dmel\TTLL5MI01917-Ex
Species
D. melanogaster
Name
FlyBase ID
FBal0391057
Feature type
allele
Associated gene
Dmel\TTLL5
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Bao et al., 2023)
Mutagen
minos activity
(Bao et al., 2023)
Progenitor genotype
Mi{MIC}TTLL5MI01917
(Bao et al., 2023, Beuchle and Suter, 2023.5.20)
Cytology
Description

Imprecise excision of the Mi{MIC}TTLL5MI01917 insertion, resulting in a 3bp insertion (CTA) that introduces a premature stop codon at the genomic position 8132 in the open-reading frame (polypeptide position 392).

(Bao et al., 2023)

Generated by imprecise excision of Mi{MIC}TTLL5MI01917, causing the formation of a premature stop codon at gene position 8,132 in the open reading frame (codon position 392).

(Beuchle and Suter, 2023.5.20)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
insertion
3R:25,114,789..25,114,790 [-]
Comment:

A 3bp insertion (CTA) that introduces a premature stop codon at the genomic position 8132 in the open-reading frame (polypeptide position 392) occurs as a result of imprecise excision of the Mi{MIC}TTLL5MI01917 insertion.

Inserted_sequence:

CTA

(Bao et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
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      Marker for
      Reflects expression of
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      Human Disease Associations
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      References
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      Disease
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      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
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      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
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      Xenogenetic Interactions
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      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TTLL5MI01917-Ex
      TTLL5MiEx
      (Bao et al., 2023, Beuchle and Suter, 2023.5.20)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)