FB2026_02 , released June 18, 2026
Allele: Dmel\HP635
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General Information
Symbol
Dmel\HP635
Species
D. melanogaster
Name
FlyBase ID
FBal0393180
Feature type
allele
Associated gene
Dmel\HP6
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Ross et al., 2013)
Progenitor genotype
P{GT1}HP6BG01429
(Ross et al., 2013)
Cytology
Description

Contains a 45bp insertion that results in a premature stop codon at the 97th codon of the HP6 open reading frame, prior to the predicted nuclear localization signal.

(Grill et al., 2023)

Imprecise excision of the P{GT1}HP6BG01429 insertion. Encodes a HP6 protein that lacks the nuclear localization signal.

(Ross et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      The lethality of the chromosome carrying the HP635 allele is genetically separable from the HP6 locus.

      (Grill et al., 2023)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HP635
      (Grill et al., 2023)
      Umbrea35
      (Ross et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)