FB2026_02 , released June 18, 2026
Allele: Dmel\CTCF::HsapCTCFhN
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General Information
Symbol
Dmel\CTCF::Hsap\CTCFhN
Species
D. melanogaster
Name
FlyBase ID
FBal0401187
Feature type
allele
Associated gene
CTCF::Hsap\CTCF
Associated Insertion(s)
TI{TI}CTCFhN
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Kamalyan et al., 2024)
cre recombinase
(Kamalyan et al., 2024)
Progenitor genotype
TI{TI}CTCFattP.mCh
(Kamalyan et al., 2024)
Associated Insertion(s)
TI{TI}CTCFhN
Cytology
Description

DNA has been re-integrated into the attP site in TI{TI}CTCFattP.mCh, resulting in a locus that expresses a chimeric protein in which the 265 amino acid N-terminus of Hsap\CTCF is fused to CTCF sequence lacking the dimerization domain (lacks residues 80-170). Some duplicated CTCF sequence (part of exon 3 through to the end of exon 4) is present downstream of the chimeric open reading frame, but this is not expressed, due to the presence of a SV40 polyadenylation signal between the reconstituted locus and the duplicated sequence. A single loxP site is present in the first intron.

(Kamalyan et al., 2024)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CTCF::Hsap\CTCFhN
      Name Synonyms
      Secondary FlyBase IDs
        References (1)