FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\His3PR(H3-H4)
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General Information
Symbol
Dmel\His3PR(H3-H4)
Species
D. melanogaster
Name
FlyBase ID
FBal0404109
Feature type
allele
Associated gene
His3
Associated Insertion(s)
Carried in Construct
PBac{12xHis.PR-1}
PBac{12xHis.PR(H3-H4)}
Key Links
Transgenic product class
silent_mutation
(Koreski et al., 2020)
wild_type
(Koreski et al., 2020)
Mutagen
Nature of the Allele
Transgenic product class
silent_mutation
(Koreski et al., 2020)
wild_type
(Koreski et al., 2020)
Mutagen
in vitro construct
(Koreski et al., 2020)
Progenitor genotype
Carried in construct
PBac{12xHis.PR-1}
PBac{12xHis.PR(H3-H4)}
Cytology
Description

His3 gene in the context of a histone gene repeat tandem array in which the entire 298bp sequence between the initiation codons of the His3 and His4 genes has been replaced with the 226bp sequence from between the initiation codons of the His2A and His2B genes. In addition, a number of synonymous mutations have been introduced into the His3 transcription unit (resulting in the addition and removal of restriction enzyme sites) so that the transgenic gene can be distinguished molecularly from the endogenous gene copies.

(Koreski et al., 2020)
Allele components
Component
Use(s)
Encoded product / tool
His3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      His3PR(H3-H4)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)