FB2026_02 , released June 18, 2026
Allele: Dmel\tsgI40E.ALFA
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General Information
Symbol
Dmel\tsgI40E.ALFA
Species
D. melanogaster
Name
FlyBase ID
FBal0404430
Feature type
allele
Associated gene
Dmel\tsg
Associated Insertion(s)
TI{TI}tsgI40E.ALFA
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Malinauskas et al., 2024)
Progenitor genotype
TI{TI}tsgattP
(Malinauskas et al., 2024)
Associated Insertion(s)
TI{TI}tsgI40E.ALFA
Cytology
Description

Sequence has been re-integrated into the attP site in TI{TI}tsgattP, reconstituting a tsg locus in which the coding sequence carries a I40E amino acid substitution and is tagged at the C-terminal end with Tag:ALFA.

(Malinauskas et al., 2024)
Allele components
Component
Use(s)
Tagged with
Tag:ALFA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
X:11,988,793..11,988,795 [-]
Nucleotide change:

ATC11988795GAR

Amino acid change:

I40E | tsg-PA

Reported amino acid change:

I40E

Comment:

An I40E amino acid substitution is included in the tsg locus sequence re-integrated into the attP site in TI{TI}tsgattP, creating a reconstituted tsg locus with an I40E amino acid substitution. Site and nature of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Malinauskas et al., 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tsgI40E.ALFA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)