FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DeltaFSH.mycmut.UAS.HRP
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General Information
Symbol
Dmel\DeltaFSH.mycmut.UAS.HRP
Species
D. melanogaster
Name
FlyBase ID
FBal0404852
Feature type
allele
Associated gene
Dmel\Delta
Associated Insertion(s)
Carried in Construct
M{UAS-FSH-HRP-Delta.mycmut}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Langridge and Struhl, 2017)
Progenitor genotype
Carried in construct
M{UAS-FSH-HRP-Delta.mycmut}
Cytology
Description

UASt sequences regulate expression of Delta in which the extracellular domain has been replaced in its entirety by Tag:LIG(FSHb) and the intracellular domain has been replaced by six copies of a mutated Tag:MYC epitope (the K residue in all six copies of the epitope has been mutated to R and the LI dipeptide that comprises a clathrin internalization signal that bypasses the requirement for Epsin has been mutated in all 6 copies). The coding sequence is tagged with HRP immediately upstream of the Delta transmembrane domain. A single FRT site is present in between the UASt and coding sequences.

(Langridge and Struhl, 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Delta
Tagged with
HRP
Tag:LIG(FSHb)
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      DeltaFSH.mycmut.UAS.HRP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)