FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Spc105RA-4A.UASp.RR
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General Information
Symbol
Dmel\Spc105RA-4A.UASp.RR
Species
D. melanogaster
Name
FlyBase ID
FBal0404931
Feature type
allele
Associated gene
Dmel\Spc105R
Associated Insertion(s)
Carried in Construct
P{UASp-Spc105R.A-4A.RR}
Key Links
Transgenic product class
missense_variant
(Joshi et al., 2024)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Joshi et al., 2024)
Mutagen
in vitro construct
(Joshi et al., 2024)
Progenitor genotype
Carried in construct
P{UASp-Spc105R.A-4A.RR}
Cytology
Description

UASp sequences regulate expression of the Spc105R A isoform, in which the RISF motif in the N-terminal region has been mutated to AAAA. The coding sequence is tagged at the C-terminal end with 6xTag:MYC. Silent mutations have been introduced to render the transgene resistant to RNAi mediated by the P{TRiP.GL00392} transgene.

(Joshi et al., 2024)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Spc105R
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Spc105RA-4A.UASp.RR
      Spc105RA-4A
      (Joshi et al., 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)