FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: SARS-CoV-2\nsp6Omicron.UAS
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General Information
Symbol
SARS-CoV-2\nsp6Omicron.UAS
Species
B. Severe acute respiratory syndrome coronavirus 2
Name
FlyBase ID
FBal0406643
Feature type
allele
Associated gene
SARS-CoV-2\nsp6
Associated Insertion(s)
Carried in Construct
P{UAS-SARS-CoV-2-nsp6.Omicron}
Transgenic product class
inframe_deletion
(Zhu et al., 2024)
missense_variant
(Zhu et al., 2024)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Zhu et al., 2024)
missense_variant
(Zhu et al., 2024)
Mutagen
in vitro construct
(Zhu et al., 2024)
Progenitor genotype
Carried in construct
P{UAS-SARS-CoV-2-nsp6.Omicron}
Cytology
Description

UASt sequences regulate expression of the SARS-CoV-2\nsp6 Omicron variant coding sequence. This contains a three amino acid deletion (L-S-G, Δ106-108) and a single amino acid variant (I189V) compared to the ancestral SARS-CoV-2\nsp6 sequence (GB sequence NC_045512, Wuhan-Hu-1 isolate).

(Zhu et al., 2024)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
SARS-CoV-2\nsp6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  Coronavirus infectious disease
      CEA
      (Zhu et al., 2024)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      This allele represents a human variant implicated in disease.
      (Zhu et al., 2024)
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      SARS-CoV-2\nsp6Omicron.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)