UAS regulatory sequences plus the Drosophila Synthetic Core Promoter (DSCP) (from the pNP vector) regulate expression of two shRNAs; the first targets Cdk8 (this hairpin contains an inverted repeat of CAAGGTGTTCCTGTTGATCGA) and the second targets kto (this hairpin contains an inverted repeat of CAGATGCTACGACAACGACAA).