FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(var)3-9330
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General Information
Symbol
Dmel\Su(var)3-9330
Species
D. melanogaster
Name
FlyBase ID
FBal0407112
Feature type
allele
Associated gene
Dmel\Su(var)3-9
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ner et al., 2002, Sinclair et al., 1983)
Progenitor genotype
Cytology
Description

Amino acid replacement: D536N.

(Ner et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:15,260,533..15,260,533 [-]
Nucleotide change:

G15260533A

Amino acid change:

D536N | Su(var)3-9-PA

Reported amino acid change:

D536N

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Ner et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      One copy of Su(var)3-9330 strongly suppresses position effect variegation (PEV) at the w locus caused by In(1)wm4.

      One copy of Su(var)3-9330 strongly suppresses the telomeric position effect (TPE) in stocks carrying a variegating P{hsp26-pt-T}39C-5 insertion at the telomere of the left arm of chromosome two.

      (Doheny et al., 2008)

      The position effect variegation of the w gene seen in In(1)wm4 flies is completely suppressed by one copy of Su(var)3-9311.

      (Ner et al., 2002)

      Phenotypic interactions exist between E(var) and Su(var) mutations. Dp(2;2)Mdh3, Su(var)330unspecified double mutants display reductions in eye pigmentation.

      (Sinclair et al., 1989)

      Dominant suppressor of position effect variegation in eye pigment caused by In(1)wm4 or In(2R)bwVDe2. Dominant suppressor of position effect variegation at the Sb locus caused by T(2;3)SbV. The suppressor effect on the variegation caused by In(1)wm4 is substantially reduced in male XO flies lacking a Y chromosome.

      (Sinclair et al., 1983)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Su(var)3-9330 is a non-suppressor of phenotype of wPD

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wEq-1

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wVG(2)A

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wPM(2)

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wPM(1)

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wP-1

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wPol-1

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wP-2

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wEq-2

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wPol-2

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wPM(3)

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wVG(2)C

      (Sun et al., 1995)

      Su(var)3-9330 is a non-suppressor of phenotype of wVG(2)B

      (Sun et al., 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      3-9330
      (Doheny et al., 2008)
      330
      (Ner et al., 2002)
      Su(var)3-9330
      (Doheny et al., 2008)
      Su(var)330
      (Sinclair et al., 1983)
      unspecified
      (Sinclair et al., 1983)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0144509
      • FBal0051878
      References (5)