FlyBase Allele Report: Hsap\PRDX2[UAS.cCa]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Hsap\PRDX2^UAS.cCa

General Information

Symbol

Hsap\PRDX2^UAS.cCa

Species

H. sapiens

Name

UAS construct a of Chua

FlyBase ID

FBal0413429

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-hPRDX2.C}

Key Links

Transgenic product class

(Chua et al., 2020)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Chua et al., 2020)

Mutagen

in vitro construct

(Chua et al., 2020)

Progenitor genotype

Carried in construct

P{UAS-hPRDX2.C}

Cytology

Description

UASt regulatory sequences drive expression of Hsap\PRDX2.

(Chua et al., 2020)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\PRDX2^UAS.cCa, Scer\GAL4^Ddc.PU is a suppressor | partially of decreased cell number | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.GFP}, Scer\GAL4^Ddc.PU

(Chua et al., 2020)

Hsap\PRDX2^UAS.cCa, Scer\GAL4^Ddc.PU is a suppressor | partially of decreased rate of adult locomotory behavior phenotype of Hsap\LRRK2^{G2019S.UAS.GFP}, Scer\GAL4^Ddc.PU

(Chua et al., 2020)

Hsap\PRDX2^UAS.cCa, Scer\GAL4^Ddc.PU is a suppressor | partially of short lived phenotype of Hsap\LRRK2^{G2019S.UAS.GFP}, Scer\GAL4^Ddc.PU

(Chua et al., 2020)

Other

Statement

Reference

Hsap\LRRK2^UAS.GFP, Hsap\PRDX2^UAS.cCa, Scer\GAL4^Ddc.PU has abnormal cell number | adult stage phenotype

(Chua et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

Hsap\PRDX2^UAS.cCa, Scer\GAL4^Ddc.PU is a suppressor | partially of adult dopaminergic neuron | decreased number phenotype of Hsap\LRRK2^{G2019S.UAS.GFP}, Scer\GAL4^Ddc.PU

(Chua et al., 2020)

Other

Statement

Reference

Hsap\LRRK2^UAS.GFP, Hsap\PRDX2^UAS.cCa, Scer\GAL4^Ddc.PU has adult dopaminergic neuron phenotype

(Chua et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\PRDX2^UAS.cCa

Name Synonyms

UAS construct a of Chua

Secondary FlyBase IDs

References (1)

Report Sections