FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term bitter-sensing neuron of labellar taste bristle ID (Ontology) FBbt:00048152 (Fly Anatomy)
Definition Gustatory receptor neuron of the labellum that responds to bitter stimuli and innervates a bitter-sensitive (short or intermediate) taste bristle. All of these cells express Gr66a, usually in combination with Gr32a, Gr33a and Gr89a (Weiss et al., 2011). Some of them also respond to high, aversive concentrations of salts (Liman et al., 2014; Freeman and Dahanukar, 2015; Jaeger et al., 2018). A subset also express TRPA1 and respond to hydrogen peroxide (Guntur et al., 2017).[ FlyBase:FBrf0212834 FlyBase:FBrf0229299 FlyBase:FBrf0229608 FlyBase:FBrf0234674 FlyBase:FBrf0240353 FlyBase:FBrf0248270 ]
Also Known As"bitter-sensing neuron of the labellum" ; "Gr66a neuron of the labellum" ; "labellar taste bristle type B gustatory receptor neuron" (for all, see Synonyms field below)
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VFB:FBbt_00048152
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Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
Insertions (FBti)PHENOTYPE_MANIFEST_IN
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 bitter-sensing neuron of labellar taste bristle (all annotations which use CV term, excluding "NOT" statements)
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labellar taste bristle sensory neuron
 |__labellar taste bristle chemosensory neuron__
high salt/bitter-sensing neuron                 |
 |__bitter-sensing neuron_______________________|
gustatory receptor neuron of the labellum       |
 |__labellar taste bristle chemosensory neuron__|
                                                bitter-sensing neuron of labellar taste bristle  15 rec.
                                                 |__broad bitter-sensing neuron of the labellum S-a 1 rec.
                                                 |__broad bitter-sensing neuron of the labellum S-b 2 rec.
                                                 |__narrow bitter-sensing neuron of the labellum I-a 1 rec.
                                                 |__narrow bitter-sensing neuron of the labellum I-b
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Is a bitter-sensing neuron
labellar taste bristle chemosensory neuron
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Synonyms
  • "bitter-sensing neuron of the labellum" EXACT
    "Gr66a neuron of the labellum" EXACT
    "labellar taste bristle type B gustatory receptor neuron" EXACT[ FlyBase:FBrf0248270 ]
    "type B GRN of labellum" EXACT[ FlyBase:FBrf0248270 ]
Secondary IDs
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FlyBrain_NDB:10381
VFB:FBbt_00048152