FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term dopaminergic PPM1 neuron ID (Ontology) FBbt:00100216 (Fly Anatomy)
Definition Dopaminergic neuron whose cell body is located in a small cluster along the dorsoventral midline of the posterior superior medial protocerebrum of the adult brain.[ FlyBase:FBrf0208427 ]
Also Known As"PPM1" ; "PPM1 cluster neuron" ; "protocerebral posteriomedial dopaminergic neuron 1" (for all, see Synonyms field below)
CommentMao and Davis (2009) identify 8 protocerebral clusters coincidentally positive for TH-GAL4 activity and tyrosine hydroxylase immunoreactivity, implying these cells are dopaminergic. They refer to the protocerebral posteriomedial dopaminergic neuron 1 as a cluster. Hartenstein et al. (2017) - FBrf0234128 show that the larval DM1 cluster (primary DPMm1/l1 lineages) becomes the adult PPM1 cluster, but unclear whether any adult cells do not derive from functional larval primary neurons.
Links to External Ontologies
VFB:FBbt_00100216
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Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Insertions (FBti)PHENOTYPE_MANIFEST_IN
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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Relevant FlyBase reports
 Alleles Split System Combinations Genes Insertions Constructs
 dopaminergic PPM1 neuron (all annotations which use CV term, excluding "NOT" statements)
     dopaminergic PPM1 neuron | adult stage
      --       --
     dopaminergic PPM1 neuron | adult stage | decreased number
      --       --       --
     dopaminergic PPM1 neuron | adult stage | increased number
      --       --       --
     dopaminergic PPM1 neuron | adult stage | progressive
      --       --       --
     dopaminergic PPM1 neuron | decreased number
      --       --
     dopaminergic PPM1 neuron | progressive
      --       --       --
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adult head
 |__adult brain______________________
adult central nervous system         |
 |__adult brain______________________|
brain                                |
 |__adult brain______________________|
dopaminergic neuron                  |
 |__adult dopaminergic neuron________|
adult neuron                         |
 |__adult CNS neuron_________________|
adult aminergic neuron               |
 |__adult dopaminergic neuron________|
CNS neuron                           |
 |__supraesophageal ganglion neuron__|
 |__adult CNS neuron_________________|
                                     dopaminergic PPM1 neuron  128 rec.
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Is a supraesophageal ganglion neuron
adult dopaminergic neuron
adult CNS neuron
Part of adult brain
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Synonyms
  • "PPM1" EXACT VFB_SYMBOL[ FlyBase:FBrf0208427 ]
    "PPM1 cluster neuron" EXACT
    "protocerebral posteriomedial dopaminergic neuron 1" EXACT
    "protocerebral posterior medial dopaminergic neuron 1" EXACT
    "TH-positive posterior medial cluster 1 neuron" EXACT
Secondary IDs
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VFB:FBbt_00100216