FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term proximal medullary amacrine neuron Pm2 ID (Ontology) FBbt:00003835 (Fly Anatomy)
Definition Proximal medullary wide-field amacrine neuron that projects along M7 and branches extensively at the M7/M8 boundary with each branch projecting into medulla layer M9 where it forms an arbor with mixed bleb-type and fine terminals (Morante and Desplan, 2008; Fischbach and Dittrich, 1989).[ FlyBase:FBrf0049410 FlyBase:FBrf0204652 ]
Also Known As"Pm2"
CommentNeurotransmitter determined to be glutamate based on vGlut[CNSIII]-GAL4 driver (FBti0129148) expression (Raghu and Borst, 2011 - FBrf0213690), but scRNAseq data assigns as GABA based on Gad1 transcripts and lineage (Konstantinides et al., 2022 - FBrf0253187). Nern et al. (2025) - FBrf0262545 identify two subtypes (Pm2a and Pm2b) in the EM data, but do not distinguish these at light level.
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VFB:FBbt_00003835
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 proximal medullary amacrine neuron Pm2 (all annotations which use CV term, excluding "NOT" statements)
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optic lobe amacrine neuron
 |__proximal medullary amacrine neuron______
adult optic lobe columnar neuron            |
 |__optic lobe wide-field columnar neuron___|
ectodermal derivative                       |
 |__anterior ectoderm derivative____________|
secondary neuron                            |
 |__Notch OFF hemilineage secondary neuron__|
Notch OFF hemilineage neuron                |
 |__Notch OFF hemilineage secondary neuron__|
medulla intrinsic neuron                    |
 |__proximal medullary amacrine neuron______|
                                            proximal medullary amacrine neuron Pm2  15 rec.
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Is a proximal medullary amacrine neuron
anterior ectoderm derivative
Notch OFF hemilineage secondary neuron
optic lobe wide-field columnar neuron
Develops from immature proximal medullary amacrine neuron Pm2
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VFB:FBbt_00003835