FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term larval PTTH neuron of pars lateralis ID (Ontology) FBbt:00007457 (Fly Anatomy)
Definition Larval neurosecretory neuron that secretes prothoracicotropic hormone (PTTH) and innervates the prothoracic gland (Siegmund and Korge, 2001; McBrayer et al., 2007). It has its soma in the cortex of the lateral protocerebrum (Siegmund and Korge, 2001). It runs along the anterior brain at the cortex/neuropil interface, forming dendritic collaterals, before traversing the midline and entering the contralateral nervus corporis cardiaci to reach the ring gland (Siegmund and Korge, 2001; Huckesfeld et al., 2021). Its peptide release sites are found in the corpus cardiacum and the prothoracic gland (Siegmund and Korge, 2001; Huckesfeld et al., 2021). It expresses corazonin receptor and has close contact with corazonin neurons in the prothoracic gland (Imura et al., 2020). There are two of these cells per hemisphere (Siegmund and Korge, 2001).[ FlyBase:FBrf0134726 FlyBase:FBrf0201640 FlyBase:FBrf0245906 FlyBase:FBrf0249161 ]
Also Known As "larval l-NSC PTTH" ; "larval prothoracic gland innervating neurosecretory neuron of the lateral protocerebrum" ; "PG neuron" (for all, see Synonyms field below)
Comment McBrayer et al. (2007) used enhancer trap expression to confirm that their PG neurons are identical to the PG-LP neurons identified by Siegmund and Korge (2001).
Links to External Ontologies
VFB:FBbt_00007457
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Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
Insertions (FBti)PHENOTYPE_MANIFEST_IN
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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 Alleles Genes Insertions Constructs
 larval PTTH neuron of pars lateralis (all annotations which use CV term, excluding "NOT" statements)
     larval PTTH neuron of pars lateralis | larval stage
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     larval PTTH neuron of pars lateralis | third instar larval stage
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supraesophageal ganglion neuron
 |__larval neurosecretory cell of pars lateralis__________
larval neuron                                             |
 |__prothoracic gland innervating neuron__________________|
 |__embryonic/larval corpus cardiacum innervating neuron__|
neurosecretory cell of pars lateralis                     |
 |__larval neurosecretory cell of pars lateralis__________|
primary neuron                                            |
 |__larval neurosecretory cell of pars lateralis__________|
larval efferent neuron                                    |
 |__larval neurosecretory cell of pars lateralis__________|
larval ring gland projection neuron                       |
 |__larval neurosecretory cell of pars lateralis__________|
neurosecretory cell of larval brain                       |
 |__larval neurosecretory cell of pars lateralis__________|
                                                          larval PTTH neuron of pars lateralis  31 rec.
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Is a prothoracic gland innervating neuron
embryonic/larval corpus cardiacum innervating neuron
larval neurosecretory cell of pars lateralis
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VFB:FBbt_00007457