FB2026_03 , released September 17, 2026
CV Term Report
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Term adult SIFamide cell of pars intercerebralis ID (Ontology) FBbt:00047427 (Fly Anatomy)
Definition Neuron of the adult pars intercerebralis (PI) that expresses SIFamide (SIFa) (Verleyen et al., 2004; Terhzaz et al., 2007). There are two of these cells per hemisphere, thought to be the only SIFamide-expressing cells of the adult central nervous system (Terhzaz et al., 2007). They innervate large parts of the brain and ventral nerve cord (Terhzaz et al., 2007), including the mushroom body calyx and alpha lobe slice 3 (Aso et al., 2014). These neurons play a role in inhibiting courtship behavior in males and reducing receptivity in females (Terhzaz et al., 2007).[ FlyBase:FBrf0179977 FlyBase:FBrf0194483 FlyBase:FBrf0224987 FlyBase:FBrf0227179 FlyBase:FBrf0248215 ]
Also Known As"SIFa" ; "SIFamide"
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VFB:FBbt_00047427
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 adult SIFamide cell of pars intercerebralis (all annotations which use CV term, excluding "NOT" statements)
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supraesophageal ganglion neuron
 |__adult neurosecretory cell of pars intercerebralis__
peptidergic neuron                                     |
 |__SIFamide cell of pars intercerebralis______________|
 |__adult peptidergic neuron___________________________|
adult neuron                                           |
 |__adult peptidergic neuron___________________________|
neurosecretory cell of pars intercerebralis            |
 |__SIFamide cell of pars intercerebralis______________|
 |__adult neurosecretory cell of pars intercerebralis__|
neurosecretory cell of adult brain                     |
 |__adult neurosecretory cell of pars intercerebralis__|
                                                       adult SIFamide cell of pars intercerebralis  11 rec.
                                                        |__descending neuron of the pars intercerebralis DNc01 6 rec.
                                                        |__descending neuron of the pars intercerebralis DNc02 5 rec.
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Is a SIFamide cell of pars intercerebralis
adult neurosecretory cell of pars intercerebralis
adult peptidergic neuron
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VFB:FBbt_00047427