FB2026_03 , released September 17, 2026
CV Term Report
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Term larval mooncrawler descending neuron ID (Ontology) FBbt:00048557 (Fly Anatomy)
Definition Cholinergic descending neuron of the larva that can induce backwards locomotion in response to touch or blue light stimuli (Carreira-Rosario et al., 2018; Omamiuda-Ishikawa et al., 2020). Its cell body is found in the ventral anterior medial brain and its processes descend to abdominal neuromeres 3-5 in the ventral nerve cord (Carreira-Rosario et al., 2018). There are two per hemisphere, which can be distinguished by their ipsilateral arbor, which is either linear (MDNa) or bushy (MDNb) (Carreira-Rosario et al., 2018). It also projects via the posterior commissure to arborize contralaterally (Carreira-Rosario et al., 2018). A large proportion of its pre-synapses are to ThDN, pair1, and A18b neurons (Carreira-Rosario et al., 2018). It persists through metamorphosis and develops into an adult moonwalker descending neuron (Carreira-Rosario et al., 2018).[ FlyBase:FBrf0239825 FlyBase:FBrf0247105 ]
Also Known As"larval MDN" ; "larval moonwalker descending neuron"
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VFB:FBbt_00048557
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 larval mooncrawler descending neuron (all annotations which use CV term, excluding "NOT" statements)
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larval neuron
 |__larval cholinergic neuron________
larval nervous system                |
 |__larval central nervous system____|
central nervous system               |
 |__larval central nervous system____|
neuron                               |
 |__primary neuron___________________|
cholinergic neuron                   |
 |__larval cholinergic neuron________|
larval descending neuron             |
 |__larval descending neuron to VNC__|
 |__larval descending neuron to SEZ__|
                                     larval mooncrawler descending neuron  3 rec.
                                      |__larval mooncrawler descending neuron a
                                      |__larval mooncrawler descending neuron b
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Is a primary neuron
larval descending neuron to VNC
larval descending neuron to SEZ
larval cholinergic neuron
Part of larval central nervous system
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VFB:FBbt_00048557