FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term adult evening cell ID (Ontology) FBbt:00049636 (Fly Anatomy)
Definition Pacemaker neuron that drives the evening locomotor activity peak (Liang et al., 2016; Yao et al., 2016; Liang et al., 2017; Delventhal et al., 2019; Liang et al., 2019). It displays a morning neural activity peak that precedes the evening locomotor activity peak (Liang et al., 2016). These cells have projections to the dorsal protocerebrum that are remodeled throughout the day (Duhart et al., 2020). They output onto the morning cells (s-LNv Pdf neurons) in this region and this connection strength varies throughout the day (Duhart et al., 2020).[ FlyBase:FBrf0231110 FlyBase:FBrf0234230 FlyBase:FBrf0235909 FlyBase:FBrf0242464 FlyBase:FBrf0243753 FlyBase:FBrf0247643 ]
Also Known As"E cell" ; "E oscillator" ; "E pacemaker" (for all, see Synonyms field below)
CommentMay be cholinergic and/or glutamatergic, but this was only shown indirectly (RNAi effect on function) (Duhart et al., 2020).
Links to External Ontologies
VFB:FBbt_00049636
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 adult evening cell (all annotations which use CV term, excluding "NOT" statements)
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pacemaker neuron__
adult neuron______|
                  adult pacemaker neuron
                   |__adult evening cell  101 rec.
                       |__adult Pdf negative s-LNv neuron 40 rec.
                       |__LNd neuron 99 rec.
                           |__adult NPF L1-s neuron (male)
                           |__CRY negative LNd neuron 2 rec.
                           |__extra LNd neuron
                           |__ITP and CRY expressing LNd neuron 5 rec.
                           |__sNPF and CRY expressing LNd neuron 1 rec.
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VFB:FBbt_00049636