FB2026_03 , released September 17, 2026
CV Term Report
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Term high salt/bitter-sensing neuron ID (Ontology) FBbt:00100044 (Fly Anatomy)
Definition A gustatory receptor neuron that is responsive to high concentrations of salt or to bitter compounds, or both (Meunier et al., 2003; Montell, 2009). It triggers an aversive behavior (Freeman and Dahanukar, 2015).[ FlyBase:FBrf0160792 FlyBase:FBrf0208984 FlyBase:FBrf0229608 ]
CommentThe projection of L2 GRNs (bitter-sensitive) of the labellum to the subesophageal zone, and of leg gustatory sensilla to the central brain are segregated from the projections of S cells (sugar-sensitive) to the thoracic ganglion (Wang et al., 2004).
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VFB:FBbt_00100044
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Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
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 high salt/bitter-sensing neuron (all annotations which use CV term, excluding "NOT" statements)
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chemosensory neuron______
gustatory system neuron__|
                         gustatory receptor neuron
                          |__high salt/bitter-sensing neuron  85 rec.
                              |__bitter-sensing neuron 36 rec.
                              |   |__bitter-sensing neuron of labellar taste bristle(+) 15 rec.
                              |   |__bitter-sensing neuron of the leg(+) 4 rec.
                              |   |__gustatory receptor neuron B2 of the terminal organ dorsolateral group 4 rec.
                              |   |__gustatory receptor neuron C1 of the terminal organ distal group 3 rec.
                              |   |__gustatory receptor neuron C7 of the terminal organ distal group
                              |   |__ventral cibarial sense organ neuron V6
                              |__Gr2a neuron of adult labral sensillum 7
                              |__gustatory receptor neuron C6 of the terminal organ distal group
                              |__high salt-sensing neuron of labellar taste bristle 7 rec.
                                  |__calcium-sensing neuron of labellar S-type taste bristle 3 rec.
                                  |__high salt-sensing neuron of labellar L-type sensillum
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VFB:FBbt_00100044