FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

mushroom body pedunculus-medial lobe arborizing neuron 1

ID (Ontology)

FBbt:00100243 (Fly Anatomy)

Definition

A neuron whose cell body is located on the inferior neuropils, lateral to the mushroom body calyx (Tanaka et al., 2008), in the dopaminergic PPL1 cluster (Aso et al., 2014). It develops from a larval mushroom body input neuron of the CP3 (DL2) lineage (Truman et al., 2023). The cell body fiber runs anteriormedially and diverges above the ellipsoid body (Tanaka et al., 2008). Its dendrite forms four main arbors, in the superior intermediate protocerebrum, superior medial protocerebrum, dorsal crepine and ventral crepine (Otto et al., 2020). Another fiber turns ventromedially and projects to the opposite hemisphere (Tanaka et al., 2008; Li et al., 2020). A third fiber (axonal) turns ventrolaterally, runs in front of the anterior surface of the gamma lobe and then below the gamma lobe, and arborizes in the spur of the gamma lobe (slice 1) and inner core of the pedunculus (Tanaka et al., 2008; Li et al., 2020; Otto et al., 2020). The contralateral fiber innervates the same mushroom body regions (Li et al., 2020). There are 1-2 neurons of this type per hemisphere (Aso et al., 2014; Li et al., 2020; Otto et al., 2020; Truman et al., 2023). It is involved in food odor attraction (Sayin et al., 2019).[ FlyBase:FBrf0205263 FlyBase:FBrf0227179 FlyBase:FBrf0243986 FlyBase:FBrf0246510 FlyBase:FBrf0248215 FlyBase:FBrf0255928 ]

Also Known As

"MB-MP1" ; "PPL1-01" ; "PPL1-gamma1pedc" (for all, see Synonyms field below)

Comment

Names are assigned according to the area of the mushroom body they arborize, as detailed in Tanaka et al. (2008). The PPL1 cluster was identified by TH immunostaining and using a TH-GAL4 driver (FBtp0020119) (Liu et al., 2012). 1-2 per hemisphere in Aso et al. (2014), 1 in FAFB, 2 (each with different larval precursor cell) in Truman et al. (2023).

Links to External Ontologies

VFB:FBbt_00100243

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Insertions (FBti)	EXPRESSION_STAGE_TISSUE_POSITION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Alleles	Split System Combinations	Insertions	Constructs
mushroom body pedunculus-medial lobe arborizing neuron 1 (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

neuron
 |__primary neuron_________________
mushroom body dopaminergic neuron  |
 |__mushroom body PPL1 neuron______|
adult DL2 lineage clone            |
 |__adult DL2 lineage neuron_______|
adult CNS neuron                   |
 |__adult DL2 lineage neuron_______|
dopaminergic PPL1 neuron           |
 |__mushroom body PPL1 neuron______|
CP3 lineage neuron                 |
 |__adult DL2 lineage neuron_______|
                                   mushroom body pedunculus-medial lobe arborizing neuron 1  78 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	primary neuron mushroom body PPL1 neuron adult DL2 lineage neuron
Develops from	larval mushroom body modulatory input neuron
Part of
Synonyms & Secondary IDs
Synonyms
	"MB-MP1" EXACT[ FlyBase:FBrf0205263 ] "PPL1-01" EXACT[ FlyBase:FBrf0227179 ] "PPL1-gamma1pedc" EXACT[ FlyBase:FBrf0227179 ] "PPL101" EXACT VFB_SYMBOL[ FlyBase:FBrf0248215 ]
Secondary IDs

External Crossreferences & Linkouts
	FlyBrain_NDB:10468 VFB:FBbt_00100243