FB2026_03 , released September 17, 2026
CV Term Report
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Term adult dopaminergic VUM neuron of the gnathal ganglion ID (Ontology) FBbt:00110128 (Fly Anatomy)
Definition Unpaired adult dopaminergic intrinsic gnathal ganglion neuron whose cell body is located ventromedially in the gnathal ganglion (Marella et al., 2012; Sterne et al., 2021). It arborizes extensively in the ventroanterior area of the gnathal ganglion with presynaptic and postsynaptic terminals (Marella et al., 2012; Sterne et al., 2021). It is involved in modulating the proboscis extension response (PER) with its activity being sufficient to trigger PER (Marella et al., 2012).[ FlyBase:FBrf0217751 FlyBase:FBrf0251280 ]
Also Known As"adult dopaminergic SB VUM neuron" ; "adult subesophageal ventral unpaired median dopaminergic neuron" ; "TH-VUM" (for all, see Synonyms field below)
CommentThe nature of the neurotransmitter was assessed by labelling cells with a tyrosine hydroxylase GAL4 driver (TH-GAL4 - FBtp0020119) and by using an antibody against tyrosine hydroxylase. Presynaptic terminals were labeled with synaptobrevin-GFP. Specific activation of the VUM neuron with UAS-TRPA1 (FBtp0040248) triggers proboscis extension. The tonic firing rate of the VUM neuron is low in conditions when the probability of proboscis extension is low (satiety) and increases in conditions when the probability of extension is high (hunger) (Marella et al., 2012).
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VFB:FBbt_00110128
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 adult dopaminergic VUM neuron of the gnathal ganglion (all annotations which use CV term, excluding "NOT" statements)
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adult brain
 |__adult dopaminergic neuron of gnathal ganglion__
neuron                                             |
 |__unpaired neuron________________________________|
gnathal ganglion neuron                            |
 |__adult dopaminergic neuron of gnathal ganglion__|
adult dopaminergic neuron                          |
 |__adult dopaminergic neuron of gnathal ganglion__|
adult central brain intrinsic neuron               |
 |__adult subesophageal zone intrinsic neuron______|
adult CNS neuron                                   |
 |__adult dopaminergic neuron of gnathal ganglion__|
                                                   adult dopaminergic VUM neuron of the gnathal ganglion  23 rec.
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Is a adult dopaminergic neuron of gnathal ganglion
unpaired neuron
adult subesophageal zone intrinsic neuron
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Synonyms
  • "adult dopaminergic SB VUM neuron" EXACT[ FlyBase:FBrf0238545 ]
    "adult subesophageal ventral unpaired median dopaminergic neuron" EXACT
    "dopaminergic VUM neuron" BROAD
    "SOG dopaminergic neuron" BROAD[ FlyBase:FBrf0217751 ]
    "TH-VUM" EXACT[ FlyBase:FBrf0217751 ]
    "tyrosine hydroxylase ventral unpaired median neuron" EXACT[ FlyBase:FBrf0251616 ]
    "VUM neuron of the dopaminergic GNG cluster" EXACT
Secondary IDs
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VFB:FBbt_00110128